Increased serum cholesterol. In children, exogenous androgens accelerate linear growth rates, but may cause a disproportionate advancement in bone maturation. RxNorm, No spontaneous pellet extrusions were reported. The degree of masculinization is related to the amount of drug given and the age of the fetus, and is most likely to occur in the female fetus when the drugs are given in the first trimester. As your body gets used to the medicine these side effects may disappear. The physician should instruct patients to report any of the following side effects of androgens: Adult or adolescent males: Too frequent or persistent erections of the penis. Long‐acting subcutaneous testosterone pellets provide sustained and steady testosterone levels for 3 to 6 months. * euphoria Biochemical Data Summary. Androgens are responsible for the growth spurt of adolescence and for the eventual termination of linear growth which is brought about by the fusion of the epiphyseal growth centers. document.write(new Date().getFullYear()) Nationwide Prescription Connection All Rights Reserved. Structural formula for testosterone follows: Each TESTOPEL® Pellet (testosterone) for subcutaneous implantation contains 75mg testosterone. * loss of appetite Copyright © 2009 International Society for Sexual Medicine. PubMed, We recognize your need for help when you are applying for discount programs for your prescription medications. Nitrogen balance is improved only when there is sufficient intake of calories and protein. * trouble breathing The implant induced cervical-uterine tumors in mice, which metastasized in some cases. Animal Data. Nervous System. Gastrointestinal. * Blurred vision Manufactured by Bartor Pharmacal * weakness in the arm or leg on one side of the body, sudden and severe Testopel (Testosterone) Manufactured By Endo Pharmaceuticals Inc. Drug Savings Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. * discouragement Infection with or without pellet extrusion, as determined by longitudinal follow‐up. There have been no reports of acute overdosage with the androgens. * lower back or side pain Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from androgens, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. * gum pain or blisters * paranoia If administered to pregnant women, androgens cause virilization of the external genitalia of the female fetus. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. Hirsutism, male pattern of baldness, and acne. NPC's mission is your health. Endogenous androgens are responsible for the normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. One pellet per vial in boxes of 10 (NDC: 43773-1001-2) and 100 (NDC: 43773-1001-3). In the face of complications where the effects of testosterone should be discontinued, the pellets would have to be removed. * swelling of the gums Androgens have been reported to increase protein anabolism and decrease protein catabolism. Androgens have been reported to stimulate the production of red blood cells by enhancing the production of erythropoietic stimulating factor. Current Drug Shortages. Events, (What If any of the following symptoms of overdose occur while taking testosterone, get emergency help immediately: & Articles, All This adverse effect may result in compromised adult stature. Endocrine and UrogenitalMale. During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). Men treated with androgens may be at an increased risk for the development of prostatic hypertrophy and prostatic carcinoma. Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia. The younger the child the greater the risk of compromising final mature height. A total of 80 men met inclusion and exclusion criteria. Androgens may decrease levels of thyroxine-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. In addition, there are times when the pellets may slough out. * Anticoagulants. * sudden and severe inability to speak This accident is usually traceable to superficial implantation or neglect in regard to aseptic precautions. * Oxyphenbutazone. Teratogenic Effects.